High-Throughput Screening Assay for Identification of Small Molecule Inhibitors of Aurora2/STK15 Kinase
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چکیده
منابع مشابه
A High Throughput Screening Assay System for the Identification of Small Molecule Inhibitors of gsp
Mis-sense mutations in the α-subunit of the G-protein, Gsα, cause fibrous dysplasia of bone/McCune-Albright syndrome. The biochemical outcome of these mutations is constitutively active Gsα and increased levels of cAMP. The aim of this study was to develop an assay system that would allow the identification of small molecule inhibitors specific for the mutant Gsα protein, the so-called gsp onco...
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ژورنال
عنوان ژورنال: Journal of Biomolecular Screening
سال: 2004
ISSN: 1087-0571,1552-454X
DOI: 10.1177/1087057104264071